Treatment of Kala-Azar with Methyl Glucamine Antimoniate
نویسنده
چکیده
a pentavalent antimony compound with the formula Sb.O-H, C7H170-N, containing 28.35 per cent of antimony. The compound makes a stable watery solution and is supplied in ampoules as a 30 per cent solution. Methyl glucamine antimoniate (MGA) is reported to be of a very low toxicity, the m.l.d. being 30 mg. per 20 gm. white mouse or about 1.5 gm. per kilo. It was found to possess curative action in experimental leishmaniasis in spermophils and in canine visceral leishmaniasis. Sohier, Pellerat and Girard (1946) were the first to try this drug in the treatment of a case of Mediterranean kala-azar and they reported
منابع مشابه
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